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Simultaneous Determination of Ethinylestradiol and Gestodene in Oral Contraceptives by Derivative Spectrophotometry

 

作者: J.J. Berzas Nevado*,   J. Rodríguez Flores,   G. Castañeda Peñalvo,   F.J. Guzmán Bernardo,  

 

期刊: Analytical Letters  （Taylor Available online 1997）
卷期: Volume 30, issue 12  

页码: 2221-2233

 

ISSN:0003-2719

 

年代: 1997

 

DOI:10.1080/00032719708001734

 

出版商: Taylor & Francis Group

 

关键词: Ethinylestradiol;Gestodene;Derivative spectrophotometry

 

数据来源: Taylor

 

摘要:

A method for determining Ethinylestradiol (ETE) and Gestodene (GTD) in mixtures by first derivative spectrophotometry is described. The measurements are made at the zero-crossing wavelengths and the calibration graphs are linear up to 38 and 22 μg/mL of ETE and GTD, respectively. The method has been applied for determining both compounds in four different Spanish commercial contraceptives.

 

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