Membranous Nephropathy: Its Relative Benignity in Women
作者:
James Hopper, Jr.,
Phillip A. Trew,
Claude G. Biava,
期刊:
Nephron
(Karger Available online 1981)
卷期:
Volume 29,
issue 1-2
页码: 18-24
ISSN:1660-8151
年代: 1981
DOI:10.1159/000182232
出版商: S. Karger AG
关键词: Membranous nephropathy;Prednisone;Nephrotic syndrome
数据来源: Karger
摘要:
By means of renal biopsy and light, immunofluorescence, and electron microscopy, a diagnosis of membranous nephropathy (MN) was made in 100 patients. The nephrotic syndrome was present in 83 of these patients. 65 of the patients were men and 35 were women. The average period of follow-up was 99.8 months. As judged by the incidence of death and of improvement or complete healing, the women fared better than the men, whether given high-dose alternate-day prednisone therapy or not. The incidence of improvement or complete healing in the patients given prednisone was higher than that reported for patients who were not given corticosteroids. We have shown that occurrence of MN is more frequent in women than men and the course of MN is more benign in women than in men; alternate-day prednisone therapy appears to be beneficial in patients with MN.
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