首页   按字顺浏览 期刊浏览 卷期浏览 Effects of cycloheximide and changes in lighting regimen on the diurnal rhythm of rat l...
Effects of cycloheximide and changes in lighting regimen on the diurnal rhythm of rat liver protein synthesis

 

作者: H. F. Krug,   R. Hardeland,  

 

期刊: Journal of Interdisciplinary Cycle Research  （Taylor Available online 1984）
卷期: Volume 15, issue 2  

页码: 119-132

 

ISSN:0022-1945

 

年代: 1984

 

DOI:10.1080/09291018409359841

 

出版商: Taylor & Francis Group

 

关键词: Circadian rhythms;cycloheximide;liver;membrane;protein synthesis;rat

 

数据来源: Taylor

 

摘要:

Under standard conditions we have demonstrated a highly significant diurnal rhythmicity of translation for both total proteins and integral membrane proteins (IMPs) using a cell‐free system from rat liver. IMPs were prepared from microsomes by treatment with EDTA and 2 M LiCl. Normal rhythmic protein synthesis of untreated rats reaches a maximum at 03.00 h and an intermediate maximum at 12.00 h for both total proteins and IMPs.

 

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