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Fetal Hepatosplenomegaly Associated with Transient Myeloproliferative Disorder in Trisomy 21

 

作者: George A. Macones,   Anthony Johnson,   Denise Tilley,   Ronald Wade,   Ronald Wapner,  

 

期刊: Fetal Diagnosis and Therapy  (Karger Available online 1995)
卷期: Volume 10, issue 2  

页码: 131-133

 

ISSN:1015-3837

 

年代: 1995

 

DOI:10.1159/000264219

 

出版商: S. Karger AG

 

关键词: Down syndrome;Hepatosplenomegaly

 

数据来源: Karger

 

摘要:

The in utero diagnosis of fetal myeloproliferative disease was made by cordocentesis following the ultrasound appearance of fetal hepatosplenomegaly and mild hydrops. The 2 fetuses reported both had leukocyte counts greater than 75,000/mm3 with a predominance of blast forms. In both cases the karyotype revealed trisomy 21.

 

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