Kidney Function and Disease in the Elderly
作者:
BeckLaurence H.,
期刊:
Hospital Practice
(Taylor Available online 1988)
卷期:
Volume 23,
issue 8
页码: 75-90
ISSN:2154-8331
年代: 1988
DOI:10.1080/21548331.1988.11703521
出版商: Taylor&Francis
数据来源: Taylor
摘要:
The major cause of age-related decline In renal function appears to be a reduction in the number of functioning nephron units, with a consequent decrease in GFR and renal blood flow. Other contributing factors may include primary tubular cell aging, reduced cardiac output with consequent renal hypoperfusion, and impaired fluid, electrolyte, and acid-base homeostasis.
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