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Monoamine Oxidase Inhibitors in General AnesthesiaA Reevaluation

 

作者: Ronald Remick,   Peter Jewesson,   Ronald Ford,  

 

期刊: Convulsive Therapy  （OVID Available online 1987）
卷期: Volume 3, issue 3  

页码: 196-203

 

ISSN:0749-8055

 

年代: 1987

 

出版商: OVID

 

关键词: Electroconvulsive therapy;Monoamine oxidase inhibitors;Anesthesia, general;Drug interactions;Phenelzine;Isocarboxazid;Tranylcypromine;Methohexital;Succinylcholine;Atropine;Adverse effects

 

数据来源: OVID

 

摘要:

A controlled study on the cardiovascular safety of monoamine oxidase inhibitors (MAOI) during general anesthesia for electroconvulsive therapy (ECT) was completed. No serious changes in blood pressure, heart rate, or ectopic beats were noted in either the MAOI or control groups during ECT. Based on pharmacological data, a review of the literature, and these preliminary results, the recommended 2-week discontinuation of MAOI before ECT appears unwarranted. Clinical guidelines for the concomitant use of MAOI and general anesthesia are offered.

 

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