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Association of Hepatitis B (HBs) Antigenaemia and Membranous Glomerulonephritis in Zimbabwean Children

 

作者: Janet Seggie,   Kusum Nathoo,   P.G. Davies,  

 

期刊: Nephron  (Karger Available online 1984)
卷期: Volume 38, issue 2  

页码: 115-119

 

ISSN:1660-8151

 

年代: 1984

 

DOI:10.1159/000183291

 

出版商: S. Karger AG

 

关键词: Hepatitis B surface antigen (HBsAg);Children;Membranous glomerulonephritis (GN);Nephrotic syndrome

 

数据来源: Karger

 

摘要:

8 Zimbabwean children are discussed in whom the nephrotic syndrome (NS) was a manifestation of membranous glomerulonephritis (GN) which was associated in every case with hepatitis B antigenaemia. This marks the first occasion that such an association has been reported in African children, although it has been thoroughly documented in children in Europe, the Far East and America. Microhaematuria, hypertension and mild to moderate renal insufficiency were frequent early associated findings, and every child exhibited hypocomplementaemia and a markedly diminished immunoglobulin G (IgG) level. The disease followed a benign course in the majority, and only 1 child died in renal failure.

 

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