Pathology of in‐stent restenosis
作者:
Renu Virmani,
Andrew Farb,
期刊:
Current Opinion in Lipidology
(OVID Available online 1999)
卷期:
Volume 10,
issue 6
页码: 499-506
ISSN:0957-9672
年代: 1999
出版商: OVID
数据来源: OVID
摘要:
The process of in-stent restenosis parallels wound healing responses. Stent deployment results in early thrombus deposition and acute inflammation, granulation tissue development, and ultimately smooth muscle cell proliferation and extracellular matrix synthesis. The severity of arterial injury during stent placement correlates with increased inflammation and late neointimal growth. These pathological findings provide useful targets for therapies aimed at reducing the incidence of in-Stent restenosis.
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