VITAMIN E DISSOLUTION IN SULFOBETAINE ZW1TTERIONIC SURFACTANT SOLUTION AND ENHANCEMENT OF DIS SOLUTION BY ADDING SODIUM CHLORIDE
作者:
Y.C. CHIU,
H.J. HWANG,
期刊:
Journal of Dispersion Science and Technology
(Taylor Available online 1999)
卷期:
Volume 20,
issue 5
页码: 1295-1318
ISSN:0193-2691
年代: 1999
DOI:10.1080/01932699908943854
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Vitamin E is widely used in pharmaceutical, food and cosmetic preparations.This paper discusses methods of preparing vitamin E emulsions by using sulfobetaine (SB) zwitterionic surfactants which have high electrolyte tolerance. The amount of vitamin E dissolved in water was analyzed by turbidity and UV absorption measurements. The emulsion droplet size was determined by laser light scattering. Microemulsions with small particle size and high resistance to oxidation in air can be obtained by solubilizing vitamin E in SB solutions at high concentrations (above %) The performance of a series of SB surfactants is compared in 1.5% solutions. A SB surfactant with a 12 carbon chain seems to be the most effective in dissolving vitamin E. The saturation value of vitamin E is increased about one order of magnitude by adding NaCl to the SB surfactant solutions. Emulsions formed in surfactant solutions containing NaCl (0 4-0.6 M) are stable at low surfactant concentrations such as 0.2-0.4 % The emulsion droplet sizes are below or around 200nm.
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