High‐frequency jet ventilation produces auto‐PEEP
作者:
WILSON,
BEAMER DONALD,
PROUGH ROGER,
ROYSTER WILLIAM,
JOHNSTON J.,
期刊:
Critical Care Medicine
(OVID Available online 1984)
卷期:
Volume 12,
issue 9
页码: 734-737
ISSN:0090-3493
年代: 1984
出版商: OVID
数据来源: OVID
摘要:
Positive-pressure ventilation can increase dead space by trapping gas, especially at high frequencies. Under conditions of high airway resistance and high pulmonary compliance, gas trapping can increase alveolar pressure without affecting proximal airway pressure, due to impedance to expiratory gas flow. The difference between alveolar pressure and proximal airway pressure at end-expiration has been called auto-PEEP. Using a mechanical test lung, we altered compliance and resistance under a variety of high-frequency jet ventilator settings to evaluate the generation of auto-PEEP. High driving pressures and prolonged inspiratory times significantly increased gas trapping. This effect was most pronounced when both airway resistance and pulmonary compliance were elevated. These findings support the concept that high-frequency jet ventilation (HFJV) may have deleterious side-effects in patients with chronic obstructive pulmonary disease.
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