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Synthesis of di‐amino‐salicil and some of its derivatives

 

作者: W. Berends,   J. M. Waisvisz,   A. K. J. Mulder,  

 

期刊: Recueil des Travaux Chimiques des Pays‐Bas  (WILEY Available online 1955)
卷期: Volume 74, issue 11  

页码: 1323-1342

 

ISSN:0165-0513

 

年代: 1955

 

DOI:10.1002/recl.19550741103

 

出版商: WILEY‐VCH Verlag

 

数据来源: WILEY

 

摘要:

AbstractFrom the work ofR. Kuhnet al. it appeared that brominated derivatives of salicil have a high anti‐bacterial activity in vitro, but that in vivo they show only little activity as a result of serum‐binding. Base‐substituted phenols are usually bound by serum to a smaller extent. Therefore, an amino‐substituted bromo‐salicil was synthesized. A water soluble derivative of this compound was also

 

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