Synthesis of di‐amino‐salicil and some of its derivatives
作者:
W. Berends,
J. M. Waisvisz,
A. K. J. Mulder,
期刊:
Recueil des Travaux Chimiques des Pays‐Bas
(WILEY Available online 1955)
卷期:
Volume 74,
issue 11
页码: 1323-1342
ISSN:0165-0513
年代: 1955
DOI:10.1002/recl.19550741103
出版商: WILEY‐VCH Verlag
数据来源: WILEY
摘要:
AbstractFrom the work ofR. Kuhnet al. it appeared that brominated derivatives of salicil have a high anti‐bacterial activity in vitro, but that in vivo they show only little activity as a result of serum‐binding. Base‐substituted phenols are usually bound by serum to a smaller extent. Therefore, an amino‐substituted bromo‐salicil was synthesized. A water soluble derivative of this compound was also
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