The Electrochemical Detection of Certain Tricyclic Drugs at Polymer Electrodes: A Preliminary Report
作者:
DouglasJ. Turk,
SamA. McClintock,
WilliamC. Purdy,
期刊:
Analytical Letters
(Taylor Available online 1985)
卷期:
Volume 18,
issue 20
页码: 2605-2618
ISSN:0003-2719
年代: 1985
DOI:10.1080/00032718508064490
出版商: Taylor & Francis Group
关键词: Polymer modified electrodes;Amitriptyline electrochemistry
数据来源: Taylor
摘要:
The development of a polymer electrode using reticulated vitreous carbon (RVC) as a support material is described. A conducting layer of (poly)carbazole or (poly)thiophene is el eletrochemically plated onto a RVC surface and the system is applied to the study of the electrochemistry of certain tricyclic drugs. An electrochemical response is seen for amitriptyline, nortriptyline and protriptyline all of which were previously reported to be electrochemically inactive while iminostilbene, imipramine and carbamazepine demonstrate similar electrochemical behaviour at both polymer and conventional carbon electrodes. The advantages of such electrodes and their use as working electrodes in hydrodynammic electrochemical detectors is presented.
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