Antipyrine disposition in calves. I. Effects of some drugs
作者:
B. O. DEPELCHIN,
S. BLODEN,
M. ANSAY,
期刊:
Journal of Veterinary Pharmacology and Therapeutics
(WILEY Available online 1987)
卷期:
Volume 10,
issue 1
页码: 49-53
ISSN:0140-7783
年代: 1987
DOI:10.1111/j.1365-2885.1987.tb00076.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Depelchin, B.O., Bloden, S.&Ansay, M. Antipyrine disposition in calves. I. Effects of some drugs. J. vet. Pharmacol. Therap.10, 49–53.The influence of four drugs on antipyrine pharmacokinetic parameters was studied after 3 h, 2 and 6 days in 32 Friesian calves. Dexamethasone phosphate and griseofulvin led to increased antipyrine elimination. The effect of dexamethasone remained significant 2 and 6 days later. The rate of antipyrine elimination was markedly but transiently depressed by chloramphenicol and oxytetracycline. The apparent volume of antipyrine distribution remained unaltered during treatmen
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