Distribution of Cystatin C (γ-Trace), an Inhibitor of Lysosomal Cysteine Proteinases, in the Anterior Lobe of Simian and Human Pituitary Glands
作者:
Christina A. Möller,
Helge Löfberg,
Anders O. Grubb,
Sven-Olle Olsson,
M. Elisabeth Davies,
Alan J. Barrett,
期刊:
Neuroendocrinology
(Karger Available online 1985)
卷期:
Volume 41,
issue 5
页码: 400-404
ISSN:0028-3835
年代: 1985
DOI:10.1159/000124209
出版商: S. Karger AG
关键词: Pituitary hormones;anterior;gonadotropins;LH;metabolism;Pituitary hormones;anterior;corticotropin;metabolism;Pituitary gland;anterior;enzymology;Protease inhibitors;Endopeptidases;Cathepsins
数据来源: Karger
摘要:
Cystatin C, a protein inhibitor of lysosomal cysteine proteinases, was demonstrated by immunohistochemical techniques to be present in most luteinizing hormone- (LH-)containing cells in simian and human adenohypophyses. Immunoreactivity of cystatin C was also found in simian adrenocorticotrophic hormone- (ACTH-)containing cells localized to an area corresponding to the pars intermedia but not in the ACTH-containing cells of the anterior pituitary lobe of monkey. No immunoreactivity of cystatin C was detected in the growth hormone- (GH-) and prolactin-containing cells of monkey and man.
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