Effect of Diets Containing Varying Concentrations of Essential Fatty Acids and Triglycerides on Renal Function in Uremic Rats and NZB/NZW F1Mice
作者:
R. Hirschberg,
D. von Herrath,
H. Klaus,
W. Höfer,
C. Schuster,
H. Rottka,
K. Schaefer,
期刊:
Nephron
(Karger Available online 1984)
卷期:
Volume 38,
issue 4
页码: 233-237
ISSN:1660-8151
年代: 1984
DOI:10.1159/000183315
出版商: S. Karger AG
关键词: Essential fatty acids;Triglycerides;Renal disease;Uremic rats;NZB/W mice
数据来源: Karger
摘要:
Influences of essential fatty acids (EFA) and triglycerides as reasons for the progression of chronic renal failure are still in debate. We studied the outcome of four diets containing different concentrations of triglycerides and EFA in 5/6 nephrectomized rats and in NZB/W mice up to 45 weeks. The results showed no significant differences in the outcome of survival rate, proteinuria, urea, and creatinine levels as well as histological findings in the different groups of both animal models. We conclude that diets containing EFA up to C18:2 or being free of EFA or that triglyceride-enriched diets have no influence on the natural course of the renal disease in these both experimental models.
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