Serum lactate dehydrogenase (LDH) activity following exposures to cadmium and/or60Co gamma irradiation
作者:
R.M. Morgan,
Y.R. Kundomal,
E.W. Hupp,
期刊:
Journal of Environmental Science and Health . Part A: Environmental Science and Engineering
(Taylor Available online 1983)
卷期:
Volume 18,
issue 4
页码: 483-492
ISSN:0360-1226
年代: 1983
DOI:10.1080/10934528309375117
出版商: Taylor & Francis Group
关键词: Lactate dehydrogenase (LDH);Lactic Acid Dehydrogenase (LDH);Cadmium;Radiation
数据来源: Taylor
摘要:
A total of 216 male Sprague‐Dawley rats were used. Animals were injected IP every 3 days for 29 days for a total of 9 injections with 0, 1.0 or 2.5 mg Cd/kg body wt. Total cumulative doses were 0, 9.0 or 22.5 mg Cd/kg body wt. Twenty‐four hrs after the last Cd injection (day 30), each animal was subjected to an acute sublethal total‐body exposure of 0, 362 or 543 rads of gamma (60Co) irradiation at a dose rate of 304 rads/min. Eight rats from each of the 9 groups were sacrificed by cardiac exsanguination on post‐irradiation day 1, 7 or 21.
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