Pinealitis coincident with recurrent uveitis: immunohistochemical studies
作者:
KalsowCarolyn M.,
DwyerAnn E.,
SmithAndrew W.,
NifongThomas P.,
期刊:
Current Eye Research
(Taylor Available online 1992)
卷期:
Volume 11,
issue sup1
页码: 147-151
ISSN:0271-3683
年代: 1992
DOI:10.3109/02713689208999525
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Although experimental models of autoimmune uveitis predict pinealitis coincident with uveitis, there is no direct evidence of pineal pathology accompanying a human uveitis. Horses with naturally occurring uveitis are a potential source of eye and pineal tissues that are not available from human patients with active uveitis. We have observed pinealitis in a mare with equine recurrent uveitis. By immunohistochemistry we demonstrated immunoglobulin and MHC Class II antigen on infiltrating and resident cells of eye and pineal gland. These results support the relevance of the animal models and suggest that pinealitis may be coincident with some human uveitides.
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