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Cold-Reacting IgM Antibody-Induced Renal Allograft Failure

 

作者: Benjamin C. Sturgill,   Peter I. Lobo,   W. Kline Bolton,  

 

期刊: Nephron  （Karger Available online 1984）
卷期: Volume 36, issue 2  

页码: 125-127

 

ISSN:1660-8151

 

年代: 1984

 

DOI:10.1159/000183131

 

出版商: S. Karger AG

 

关键词: Renal transplantation;IgM antibody;Cold agglutinins;Hyperacute rejection

 

数据来源: Karger

 

摘要:

Hyperacute rejection of renal allografts is usually mediated by IgG antibody, but recent studies indicate that cold-reacting IgM alloantibodies are also associated with immediate malfunction of renal allografts. We report 2 cases of cold-reacting IgM-mediated allograft malfunction in which immediate posttransplant biopsies resembled hyperacute rejection. This reaction can probably be prevented by warming the kidney just before transplantation.

 

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