BACKGROUND- The various off-label applications of clonazepam in neurology are summarized to provide an accessible source of clinical information for the neurology practitioner.REVIEW SUMMARY- Although clonazepam is only approved by the Food and Drug Administration as an anti-epileptic drug, it can be prescribed for the treatment of movement disorders, neuropathic pain, sleep-associated disorders, and nystagmus-induced oscillopsia. The pharmacology of clonazepam, the doses used in these various unapproved indications, and the side effect and drug interaction profile are also summarized.CONCLUSIONS- Knowledge of clonazepam off-label indications would enable practitioners to prescribe it as an alternative in the management of these neurologic disorders.