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Effect of Methotrexate, Kenalog, and Cyclophosphamide on the Antibody Response of Steelheads to Aeromonas salmonicida

 

作者: MartinF. Chen,   J.S. Rohovec,   J.L. Fryer,  

 

期刊: Transactions of the American Fisheries Society  (Taylor Available online 1983)
卷期: Volume 112, issue 4  

页码: 561-564

 

ISSN:0002-8487

 

年代: 1983

 

DOI:10.1577/1548-8659(1983)112<561:EOMKAC>2.0.CO;2

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

Methotrexate, kenalog, and cyclophosphamide were tested for immunosuppressive activity in steelheads Salmo gairdneri. Three 60-mg/kg injections of methotrexate prevented an increase in serum antibody titer in fish previously immunized with killed whole cells of Aeromonas salmonicida. No immunosuppression in previously immunized steelheads was observed following injections of kenalog and cyclophosphamide.

 

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