Methadone Maintenance Therapy for Opioid DependenceA Guide to Appropriate Use
作者:
Jeff Ward,
James Bell,
Richard P. Mattick,
Wayne Hall,
期刊:
CNS Drugs
(ADIS Available online 1996)
卷期:
Volume 6,
issue 6
页码: 440-449
ISSN:1172-7047
年代: 1996
出版商: ADIS
数据来源: ADIS
摘要:
Opioid dependence is a chronic, relapsing condition that is associated with significant morbidity and mortality. Methadone maintenance therapy involves the provision of a controlled supply of an orally administered opioid, thereby stabilising the opioid-dependent patient. Research studies have shown that methadone maintenance reduces illicit opioid use, opioid-related crime, premature mortality and the risk of HIV infection. It is most effective when prescribed at an adequate dosage (usually 60 to 100 mg/day) and when long term maintenance on methadone is the goal of treatment rather than detoxification from all drugs including methadone. Successful long term methadone maintenance is more likely when it takes place within the context of a well established therapeutic relationship and when the medical, social and psychological needs of patients are met either through direct assistance or referral.
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