PATHOLOGICAL CHANGES FOLLOWING EXPERIMENTAL OBSTRUCTION OF THE COMMON BILE DUCT, HEPATIC BILE DUCT AND HEPATIC ARTERY IN THE SHEEP AND THEIR RELATION TO FACIAL ECZEMA
作者:
DD Leaver,
GS Christie,
期刊:
Australian Journal of Experimental Biology and Medical Science
(WILEY Available online 1965)
卷期:
Volume 43,
issue 1
页码: 1-16
ISSN:0004-945X
年代: 1965
DOI:10.1038/icb.1965.1
出版商: Nature Publishing Group
数据来源: WILEY
摘要:
SummaryPathological changes in the sheep following ligation of the hepatic bile duct, combined ligation of both the hepatic bile duct and the branch of the hepatic artery to the ventral lobe, ligation of the common bile duct and ligation of the hepatic artery to the ventral lobe, are described and discussed. It was demonstrated that a combination of obstruction of the biliary drainage and a considerable decrease of the blood How was required to produce the maximum degree of bile ductule proliferation and parenchymal atrophy seen in the chronic stage of facial eczema in the sheep. Obstruction of the common bile duct did not reproduce the liver changes of facial eczema. Although evidence is cited in the sheep, which suggests that some degree of interference with blood supply followed ligalion of the hepatic duct only, the lesion produced was not comparable in degree to that of facial eczema.
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