Type IV Hyperlipoproteinemia in a Consanguinous Family
作者:
Morteza Amidi,
期刊:
Circulation
(OVID Available online 1972)
卷期:
Volume 45,
issue 5
页码: 988-990
ISSN:0009-7322
年代: 1972
出版商: OVID
关键词: Gout;Triglycerides;Xanthinoxidase inhibitor;Atromid-S;Xanthoma
数据来源: OVID
摘要:
The involvement of all five offspring of consanguinous and hypertriglyceridemic parents (first cousins) is reported.Three sons and two daughters of this family have increased triglycerides, normal cholesterol, and normal or slightly increased phospholipids. Mother and elder daughter have abnormal glucose tolerance. Father and mother are hypertensive; father had recent development of myocardial infarction and gout. The two elder sons had myocardial infarction and repeated bouts of angina. All three male offspring of this family have gout and are being treated with xanthinoxidase inhibitor (allopurinol). Planar xanthoma was present in one son with myocardial infarction. No chylomicronemia was noted. The response to diet and Atromid-S was satisfactory.
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