Male meiosis and gametogenesis in wild house mice (Mus musculus domesticus) from a chromosomal hybrid zone; a comparison between “simple” Robertsonian heterozygotes and homozygotes
作者:
B.M.N. Wallace,
J.B. Searle,
C.A. Everett,
期刊:
Cytogenetic and Genome Research
(Karger Available online 1992)
卷期:
Volume 61,
issue 3
页码: 211-220
ISSN:1424-8581
年代: 1992
DOI:10.1159/000133410
出版商: S. Karger AG
数据来源: Karger
摘要:
Wild male house mice Mus musculus domesticus were collected from the hybrid zone between the John o’Groats race (2n = 32) and the standard race (2n = 40) in northern Scotland. Meiosis in both homozygotes (2n = 32, 36, and 40) and single Robertsonian heterozygotes (2n = 33, 35, and 37) was found to be orderly. At prophase/metaphase I in heterozygotes, a trivalent was formed from the metacentric and two homologous acrocentrics. At pachytene, this trivalent usually had a single side arm at the position of the centromeres, as a result of nonhomologous pairing of the acrocentrics. This side arm persisted into diplotene. Generally only a single chiasma was formed between each acrocentric and the metacentric. Ana-phase I nondisjunction frequencies were estimated as 1.5% for the homozygotes and 2.7% for the heterozygotes. The extent of germ cell death between the pachytene and round spermatid stages was 18 % greater in heterozygotes than in homozygotes. Our results concur with previous studies which indicate that single Robertsonian heterozygotes in wild house mice have near-normal fertilit
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