Carboplatin-based chemotherapy in patients with gynecological malignancies on long-term hemodialysis
作者:
Hitoshi Niikura,
Toshimitsu Koizumi,
Kiyoshi Ito,
Kunihiro Okamura,
Nobuo Yaegashi,
期刊:
Anti-Cancer Drugs
(OVID Available online 2003)
卷期:
Volume 14,
issue 9
页码: 735-738
ISSN:0959-4973
年代: 2003
出版商: OVID
关键词: carboplatin;endometrial carcinoma;hemodialysis;ovarian carcinoma;paclitaxel
数据来源: OVID
摘要:
We report on three cases of long-term dialysis patients with gynecological malignancies who were successfully treated with chemotherapy. Two epithelial ovarian carcinoma patients were treated with a single agent, carboplatin (100–200 mg/m2). One recurrent endometrial carcinoma patient was treated with carboplatin (200 mg/m2) and paclitaxel (135 mg/m2). Hemodialysis was started 2 h after the carboplatin infusion and lasted 4 h in all three cases. All patients tolerated these therapies without significant myelosuppression or severe side-effects. Our findings suggest these regimens are feasible, and the combination of paclitaxel and carboplatin is effective chemotherapy when administered to long-term hemodialysis patients with recurrent endometrial carcinoma.
点击下载:
PDF
(63KB)
返 回