Leuprolide suppression of androgen secretion by hilus cell hyperplasia within the wall of an ovarian cyst
作者:
Manuel De Santiago,
Lucrecia Herranz,
Juan Ordas,
Miguel Atienza,
Maria Suarez‐Mier,
Pilar G. Gancedo,
期刊:
Clinical Endocrinology
(WILEY Available online 1996)
卷期:
Volume 45,
issue 2
页码: 239-242
ISSN:0300-0664
年代: 1996
DOI:10.1046/j.1365-2265.1996.d01-1549.x
出版商: Blackwell Science Ltd
数据来源: WILEY
摘要:
Androgenic manifestations coexisting with hilus cell hyperplasia adjacent to a tumour or an ovarian cyst are extremely rare. We report the case of a post‐menopausal woman with hirsutism associated with hilus cell hyperplasia within the wall of an ovarian cyst. The pattern of steroid secretion revealed increased testosterone release. Suppression of testosterone to ‘normal range’ was seen in response to leuprolide administration. This new approach demonstrates gonadotrophin dependence of hilus cell hyperplasia within an ovarian
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