Rehabilitation patients who will undergo noncardiac surgery or strenuous rehabilitation programs often cannot exercise to greater than 85% of predicted maximal heart rate as required for valid treadmill testing. Because many patients have known or suspected coronary artery disease, greatly increasing their risk for a cardiac event, dipyridamole thallium scans are usually performed, despite a cost of approximately $1400, patient radiation exposure, and the need for a gamma camera. Instead, arm-leg cycle stress testing can be continued to an appropriately high heart rate, is done in the physician's office with an electrocardiograph machine and a blood pressure cuff, and costs $250. This study describes nine patients who had both dipyridamole thallium scans and arm-leg cycle ergometry. Four awaited peripheral vascular surgery, one needed bilateral knee replacements, one was an amputee, and three had claudication. Six had documented and three had suspected coronary disease.RESULTS:In eight of nine patients, the electrocardiograms during both dipyridamole thallium imaging and ergometry were in agreement as to the presence or absence of ischemia (kappa statistic, 0.7273;P= 0.0117). In seven of nine patients, thallium images and ergometry agreed (78% concurrence). To achieve 90% agreement between dipyridamole thallium scans and cycle results, however, 68 patients would have to be studied.CONCLUSION:In this preliminary study, arm-leg ergometry was feasible in all patients and seemed cost-effective and useful for detecting myocardial ischemia. Clinically, if the ergometry were inconclusive, dipyridamole thallium scans could be performed subsequently to obtain the needed information.