In the application of factorial experiments in industry, it is often necessary to apply the factors sequentially. For 2pexperiments in which (a) multiple testing on each experimental unit is possible and not degrading, (b) the effects of the factors are permanent, and (c) the low level of a factor is the absence of that factor, a design and an analysis are presented which allow the estimation and testing of order effects as well as the usual main and interaction effects of the factors.