Update Thyroid-Associated Ophthalmopathy
作者:
WeetmanA. P.,
期刊:
Autoimmunity
(Taylor Available online 1992)
卷期:
Volume 12,
issue 3
页码: 215-222
ISSN:0891-6934
年代: 1992
DOI:10.3109/08916939209148462
出版商: Taylor&Francis
关键词: Graves' disease;thyroid-associated ophthalmopathy;eye muscle
数据来源: Taylor
摘要:
Thyroid-associated ophthalmopathy (TAO) is one of the most vexing problems in endocrinology but its relationship to thyroid autoimmunity is becoming more clear with the realisation that almost all patients with Graves' disease have this condition and almost all patients with ophthalmopathy have some form of thyroid involvement. This suggests cross reactivity between thyroid and retrobulbar antigens, of which one potential candidate has recently been cloned. Together with new information on predisposing factors and the important role of the retrobulbar fibroblasts, these developments shed new light on the aetiology and pathogenesis of this enigmatic disorder.
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