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Tardive Dyskinesia Among Chinese and Malay Patients With Schizophrenia

 

作者: Siow-Ann Chong,   Rathi Mahendran,   David Machin,   Hong-Choon Chua,   Gordon Parker,   John Kane,  

 

期刊: Journal of Clinical Psychopharmacology  (OVID Available online 2002)
卷期: Volume 22, issue 1  

页码: 26-30

 

ISSN:0271-0749

 

年代: 2002

 

出版商: OVID

 

数据来源: OVID

 

摘要:

The prevalence of tardive dyskinesia (TD) was studied with the Abnormal Involuntary Movements Scale in Chinese and Malay patients with schizophrenia who were hospitalized in a Singapore state psychiatric institute. We also studied the relationship of neuroleptic-induced extrapyramidal side effects to TD. By using established criteria, the rates of TD were 40.6% for Chinese and 29.0% for Malays, higher than previously reported for Chinese subjects. Older age and lower current neuroleptic dose were significantly associated with TD. Multivariate analysis, after controlling for other salient risk variables, did not show a significant difference in TD prevalence rates between the two races. We conclude that suggested differences in interethnic rates of TD among Chinese, Malays, and Westerners are unlikely to exist and that any variation in prevalence is more likely to be determined by differences in duration of exposure and dose levels of neuroleptic drugs.

 

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