Phosphate supplementation for hypophosphataemia and parenteral nutrition
作者:
William Hicks,
Gil Hardy,
期刊:
Current Opinion in Clinical Nutrition and Metabolic Care
(OVID Available online 2001)
卷期:
Volume 4,
issue 3
页码: 227-233
ISSN:1363-1950
年代: 2001
出版商: OVID
数据来源: OVID
摘要:
Routine detection and treatment of acute hypophosphataemia is important in intensive care unit and many other hospitalized patients, but metabolic bone disease and hypophosphataemia are still experienced as a result of parenteral nutrition. A significantly common problem that faces the compounding pharmacist when formulating parenteral nutrition regimens is the difficulty associated with the successful avoidance of calcium phosphate precipitation. Although incorporation of the normal calcium and phosphate requirements into regimens for metabolically stable adults is usually achievable, it can prove impossible in paediatric and neonatal mixtures when using the standard inorganic sources that are currently licensed for use in the UK and USA. In other countries, where organic compounds are routinely available, this problem does not exist.
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