The design of a clinical trial when there are two categories of patients
作者:
Allan Donner,
期刊:
Canadian Journal of Statistics
(WILEY Available online 1976)
卷期:
Volume 4,
issue 1
页码: 95-108
ISSN:0319-5724
年代: 1976
DOI:10.2307/3315265
出版商: Wiley‐Blackwell
关键词: Clinical trial;two categories of patients;Bayes rule;pooling strategy;expected net gain.
数据来源: WILEY
摘要:
AbstractStrategies are investigated for selecting one of two medical treatments when patients may be stratified into two distinct categories on the basis of their expected difference in response to the two treatments. The relative effectiveness of the following three strategies are assessed: (1) separate decisions made independently for the two categories, (2) a single overall decision made on the basis of simple pooling, and (3) the Bayes strategy.
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