Inhibition of Spontaneous Contractile Activity in Isolated Human Detrusor Muscle Strips by Vasoactive Intestinal Polypeptide
作者:
R. B. KINDER,
A. R. MUNDY,
期刊:
British Journal of Urology
(WILEY Available online 1985)
卷期:
Volume 57,
issue 1
页码: 20-23
ISSN:0007-1331
年代: 1985
DOI:10.1111/j.1464-410X.1985.tb08976.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Summary—In a study of 75 isolated human detrusor muscle strips, spontaneous contractions and an associated sustained rise in basal tension were observed in 43 (57%). Vasoactive intestinal polypeptide (VIP) caused significant reductions in the frequency and amplitude of spontaneous contractions and a fall in basal tension. The results suggest that VIP may have a role as an inhibitor of spontaneous activity in the human detruso
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