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Possible association of human growth hormone treatment with an occurrence of acute myeloblastic leukemia with an inversion of chromosome 3 in a child of pituitary dwarfism

 

作者: Machiko Endo,   Yasuhiko Kaneko,   Takaaki Shikano,   Hideki Minami,   Jun‐Ichi Chino,  

 

期刊: Medical and Pediatric Oncology  （WILEY Available online 1988）
卷期: Volume 16, issue 1  

页码: 45-47

 

ISSN:0098-1532

 

年代: 1988

 

DOI:10.1002/mpo.2950160111

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

关键词: acute nonlymphocytic leukemia;thyroxine;abnormal karyotype

 

数据来源: WILEY

 

摘要:

AbstractAn 11–yr‐old girl, who had been treated with human growth hormone (h‐GH) for 31 months, developed acute myeloblastic leukemia with an inv(3)(q21q26). Since CH has been suggested to influence the genesis of leukemia, and the inversion 3 has been reported only in adult leukemia patients, the GH treatment may have caused the development of leukemia or accelerated the proliferation of the leukemia

 

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