首页   按字顺浏览 期刊浏览 卷期浏览 A new synthetic functionalized antigen carrier
A new synthetic functionalized antigen carrier

 

作者: J. W. DRIJFHOUT,   W. BLOEMHOFF,  

 

期刊: International Journal of Peptide and Protein Research  （WILEY Available online 1991）
卷期: Volume 37, issue 1  

页码: 27-32

 

ISSN:0367-8377

 

年代: 1991

 

DOI:10.1111/j.1399-3011.1991.tb00729.x

 

出版商: Blackwell Publishing Ltd

 

关键词: multiple antigenic peptide (MAP);3‐nitro‐2‐pyridinesulfenyl (NPys);solid‐phase peptide synthesis;unsymmetrical disulfide formation

 

数据来源: WILEY

 

摘要:

A new synthetic functionalized antigen carrier is described. It consists of a core of seven branched lysine residues, of which each of the fourN‐terminal lysine residues contains twoN‐(S‐acetylmercaptoacetyl)‐glutamyl residues. After removal of the protectingS‐acetyl groups affording eight thiol functions, the carrier can easily be conjugated to a properly functionalized antigen, e.g. anS‐(Npys)‐cysteinyl peptide, thus affording a high molecular weight conjugate with an unusually high an

 

点击下载:  PDF (442KB)



返 回