Hepatitis C Virus in Dialysis Units: A Multicenter Study
作者:
A. Da Porto,
A. Adami,
F. Susanna,
P. Calzavara,
P. Poli,
M.R. Castelletto,
G.P. Amici,
T. Teodori,
L. Okolicsanyi,
期刊:
Nephron
(Karger Available online 1992)
卷期:
Volume 61,
issue 3
页码: 309-310
ISSN:1660-8151
年代: 1992
DOI:10.1159/000186916
出版商: S. Karger AG
关键词: Hepatitis C virus;Hemodialysis
数据来源: Karger
摘要:
Three hundred and eighty-seven chronic hemodialysis patients were evaluated, in a multicenter study, to investigate the epidemiology of hepatitis C virus. In anti-HCV seropositive patients, serum ALT values and blood transfusions were retrospectively compared; blood donors were studied for serum transaminases. In seropositive patients without previous blood transfusions, analysis of dialysis schedule was done. Eventually, the intrafamilial transmission of hepatitis C virus was studied in 104 family members. The prevalence of HCV infection in hemodialysis patients was 15.7%. The incidence of acute hepatitis was frequent, while chronic hepatitis incidence was less than expected (17.5%). Intrafamilial diffusion was low (1.9%). Blood-transfusion-related infections seem to be negligible, while cross-contamination in dialysis units seems to be very important.
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