Short CommunicationCystic Fibrosis “Factor(s)” Present Also in Sera of Shwachman's Pancreatic Insufficiency
作者:
G. BANCHINI,
J. HARRIES,
P. MILLA,
D. MULLER,
E. ROMA,
J. TRIPP,
期刊:
Pediatric Research
(OVID Available online 1981)
卷期:
Volume 15,
issue 7
页码: 1073-1075
ISSN:0031-3998
年代: 1981
出版商: OVID
关键词: cystic fibrosis;intestine;cystic fibrosis-factor;Shwachmann's;exocrine pancreatic insufficiency;syndrome
数据来源: OVID
摘要:
SummaryUsing anin vivoclosed-loop technique in rat jejunum, we have confirmed previousin vitrostudies that cystic fibrosis (CF) serum inhibits water, sodium, and glucose absorption and transmural potential difference. CF heterozygote serum or sera from children with diarrhoeal disorders not associated with exocrine pancreatic insufficiency had no effect on transport. Sera from patients with Shwachman's syndrome and exocrine pancreatic insufficiency had identical effects to CF serum. These results challenge the specificity of the CF “factor.”
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