Cerebrovascular Risk Factors and Depression in Older Primary Care PatientsTesting a Vascular Brain Disease Model of Depression
作者:
Jeffrey Lyness,
Eric Caine,
Deborah King,
Yeates Conwell,
Christopher Cox,
Paul Duberstein,
期刊:
American Journal of Geriatric Psychiatry
(OVID Available online 1999)
卷期:
Volume 7,
issue 3
页码: 252-258
ISSN:1064-7481
年代: 1999
出版商: OVID
关键词: Depression;Cerebrovascular Factors;Syndromes Secondary to General Medical Disorders;Primary Care Patients
数据来源: OVID
摘要:
The authors examined whether cerebrovascular risk factors (CVRFs) are associated with depressive diagnoses and symptoms in 303 primary-care patients age ≥60 years, as would be consistent with a small-vessel brain disease model of later-life depression. CVRFs were not significantly independently associated with major, minor, or subsyndromal depression, late-onset major depression, or overall depressive symptom severity. These data did not support the notion that a small-vessel brain disease model of depression might apply to the majority of older persons with depressive symptoms and syndromes in primary-care settings. Future work should include longitudinal study with larger sample sizes.
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