A Double-Blind Amino Acids, L-Tryptophan and L-Tyrosine, and Placebo Study with Cocaine-Dependent Subjects in an Inpatient Chemical Dependency Treatment Center
作者:
ChadwickMichael J.,
GregoryDavid L.,
WendlingGlenda,
期刊:
The American Journal of Drug and Alcohol Abuse
(Taylor Available online 1990)
卷期:
Volume 16,
issue 3-4
页码: 275-286
ISSN:0095-2990
年代: 1990
DOI:10.3109/00952999009001589
出版商: Taylor&Francis
数据来源: Taylor
摘要:
In a six-month double-blind study in an inpatient chemical dependency facility, 29 cocaine-dependent subjects were studied to determine if the amino acids, L-tryptophan and L-tyrosine, would decrease cocaine craving and withdrawal symptoms. Those subjects receiving placebo were shown to have a statistically significant increase in only one physical symptom category. The drug craving and other major physical and subjective symptoms were not shown to be significant. This study is consistent with a literature review in demonstrating that the amino acids do not significantly reduce most symptoms of cocaine craving and withdrawal when used alone.
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