Experience sampling is a relatively new research approach that captures relevant variations in experince and symptoms in the course of everday life. In this paper, a socioecological frame of reference that integrates psychological, historical, cultural, and develop mental theories about anxiety phenomena will be illustrated using quantitative descriptions of anxiety and avoidance behaviors gathered with the Experience-Sampling Method. The interaction between anxiety symptoms and the environment in which they occurred is explored in a case study that points to possibilities for future research and the establishment of therapeutic approaches that are optimally suited to the individual patient.