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A review of the molecular mechanism of HSV-1 latency

 

作者: FraserN. W.,   SpivackJ. G.,   WroblewskaZ.,   BlockT.,   DeshmaneS. L.,   ValyiT.,   NatarajanR.,   GesserR. M.,  

 

期刊: Current Eye Research  (Taylor Available online 1991)
卷期: Volume 10, issue sup1  

页码: 1-13

 

ISSN:0271-3683

 

年代: 1991

 

DOI:10.3109/02713689109020352

 

出版商: Taylor&Francis

 

数据来源: Taylor

 

摘要:

The neurotropic herpes viruses, as typified by herpes simplex virus type 1, are noted for their ability to form latent infections. The latent infection differs from the acute infection both in gene expression and the physical state of the viral genome. Latency can be divided into several stages - establishment, maintenance of reactivation - each of which are active areas of research. This review describes the molecular biology of HSV-1 latency and presents the current level of understanding of the molecular mechanism of HSV-1 latency.

 

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