Classification of adverse reproductive effects can be improved by measurements of multiple biomarkers for ovarian toxicity and early fetal loss
作者:
B. L. Lasley,
E. B. Gold,
S. T. Nakajima,
D. R. Stewart,
J. W. Overstreet,
期刊:
Journal of Toxicology and Environmental Health
(Taylor Available online 1993)
卷期:
Volume 40,
issue 2-3
页码: 423-433
ISSN:0098-4108
年代: 1993
DOI:10.1080/15287399309531809
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Hormone assays have been developed and applied for monitoring reproductive function using self‐collected urine samples in non‐clinical populations of women. Early pregnancy loss, menstrual dysfunction, reduced fertility as well as the site of toxicity can now be assessed using daily early morning urine samples. The understanding of the specific limitations of individual assay systems is important, however, to make the best use of these systems. The use of multiple end‐points and computer algorithms is suggested to avoid misclassification of adverse reproductive events.
点击下载:
PDF (687KB)
返 回