A simple treatment of gelatin granules with aqueous glutaraldehyde (GLA) yields a versatile crosslinked matrix. The crosslinking involves the ε-amino groups of the lysine residues of the protein and the aldehyde functionality of the GLA. Grafting of this matrix with methyl acrylate results in a very interesting material which has a hydrophilic core but anchors hydrophobic grafts. Here we report the preparative details and essential characteristics of this versatile graft copolymer.