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Potential affinity and photoaffinity reagents for the membrane protein of human erythrocytes involved in glucose transport. Synthesis of 6-amino-6-deoxy derivatives ofD-glucose

 

作者: Mohabir Ramjeesingh,   Arthur Kahlenberg,  

 

期刊: Canadian Journal of Chemistry  (NRC Available online 1977)
卷期: Volume 55, issue 21  

页码: 3717-3720

 

ISSN:0008-4042

 

年代: 1977

 

DOI:10.1139/v77-522

 

出版商: NRC Research Press

 

数据来源: NRC

 

摘要:

From 1,2-O-isopropylidene-α-D-glucofuranose1, the 6-amino-6-deoxy-l,2:3,5-di-O-isopropylidene-α-D-glucofuranose6was prepared in a four-step sequence in an overall 50% yield. The conversion of6to the 6-bromoacetamido-6-deoxy10, 6-deoxy-6-isothiocyanato11, and 6-(p-azido-o-nitroanilino)-6-deoxy12derivatives ofD-glucose is described.

 

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