Synthesis of B1 Substituted Peptidyl InsulinsThe peptide derivatives Boc‐Leu‐Tyr(Bzl)‐Gln‐Leu‐OHNomenklatur und Abkürzungen nach den Regeln der IUPAC‐IUP‐Commission on Biochemical Nomenclature: Hoppe‐Seyler's Z. Physiol. Chem.348(1967) 256 und J. Biol. Chem.247(1972) 977.of the sequence section 13–16 of the insulin A chain and Boc‐Leu‐Tyr(Bzl)‐Leu‐Val‐Cys(SEt)‐Gly‐OH corresponding to the partial sequence 15–20 of the B chain are condensated with A1, B29‐Boc2‐insulin via their pentachlorphenylesters. After removal of the protecting groups by HBr/TFA in the presence of anisole and ethylmercaptan the corresponding insulins elongated in position B1