Selected ion monitoring assay for meclizine in human plasma
作者:
Hassan G. Fouda,
Fred C. Falkner,
Donald C. Hobbs,
Elbridge W. Luther,
期刊:
Biological Mass Spectrometry
(WILEY Available online 1978)
卷期:
Volume 5,
issue 8
页码: 491-494
ISSN:0306-042X
年代: 1978
DOI:10.1002/bms.1200050806
出版商: Wiley Subscription Services, Inc., A Wiley Company
数据来源: WILEY
摘要:
AbstractA method has been developed for the quantification of meclizine in human plasma using gas chromatography mass spectrometry. Pentadeuterated meclizine was synthesized and used as an internal standard. The method gave linear results over a concentration range of 5–200 ng ml−1and was used to determine plasma levels of meclizine following administration to a male volunt
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