Topics in Clinical PharmacologyFlumazenil, a Benzodiazepine Antagonist
作者:
ATKINSON LONGMIRE,
DONNA SEGER,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 1993)
卷期:
Volume 306,
issue 1
页码: 49-52
ISSN:0002-9629
年代: 1993
出版商: OVID
关键词: Flumazenil;Benzodiazepines;Antagonists
数据来源: OVID
摘要:
Flumazenil is a central antagonist of the sedative effects of benzodiazepines. It has been used to reverse benzodiazepine effects in conscious sedation, general anesthesia, and overdose with restoration of alertness and psychomotor function within minutes of administration. Seizures have followed the use of flumazenil. Overdose patients who have co-ingested cyclic antidepressants are especially at risk for this complication. Flumazenil is administered intravenously in small, incremental doses.
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