The underlying causative agent in the majority of patients with chronic liver disease is ethanol; the rest of the cases are largely viral in aetiology (hepatitis B or C viruses). Nutrition supplementation improves the quality of life and decreases morbidity in chronic liver disease, but evidence that it prolongs long-term survival is lacking. The situation is very different in chronic liver disease patients who receive a liver transplant, however, with better pretransplantation nutrition status predicting a distinctly improved survival after transplantation.