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Synthesis of Peptides Containing α,α‐Disubstituted α‐Amino Acids by the Azirine/Oxazolone Method: The (12–20)‐Nonapeptide of the Ionophore Alamethicin

 

作者: Peter Wipf,   Heinz Heimgartner,  

 

期刊: Helvetica Chimica Acta  （WILEY Available online 1990）
卷期: Volume 73, issue 1  

页码: 13-24

 

ISSN:0018-019X

 

年代: 1990

 

DOI:10.1002/hlca.19900730103

 

出版商: WILEY‐VCH Verlag GmbH

 

数据来源: WILEY

 

摘要:

AbstractThe (12–20)‐nonapeptide Z‐Leu‐Aib‐Pro‐Val‐Aib‐Aib‐Glu (OBzl)‐Gln‐Pheol (10) of the ionophor alamethicin was synthesized by a new strategy, using 3‐amino‐2,2‐dimethyl‐2H‐azirines 2 as synthons for the α‐a

 

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