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X‐Ray conformational study of hydrazino peptide analogues

 

作者: André Aubry,   Daniel Bayeul,   Jean‐Paul Mangeot,   Joëlle Vidal,   Sébastien Sterin,   André Collet,   Alain Lecoq,   Michel Marraud,  

 

期刊: Biopolymers  （WILEY Available online 1991）
卷期: Volume 31, issue 6  

页码: 793-801

 

ISSN:0006-3525

 

年代: 1991

 

DOI:10.1002/bip.360310625

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

数据来源: WILEY

 

摘要:

AbstractWe have solved the crystal structures of nine pseudo‐peptide analogues deriving from the hydrazino analogue of glycine or valine (NβH2‐NαH‐CαHR‐CO2H, R = H or iPr) or proline (NβH2‐Nα‐CαH‐CO2H) and containing the hydrazide (CO‐NβH‐Nα) or Nβ‐Z‐aminoamide peptidomimetic link. This study gives access to the average geometry of these two links, to their inter‐ and intramolecular interaction modes, and to their influence on the conformati

 

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